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Mini In-Vitro Fertilization (IVF)

Mini IVF

A Cutting-Edge, Minimally Obtrusive Fertilization Method in San Diego

Minimal Stimulation IVF (Mini IVF) is an approach to IVF that focuses on prioritizing quality, safety, comfort and success. We have adopted Japanese protocols because they are structured around retrieving the highest quality eggs, which can then be used to create a high-quality embryo, which can then be returned to an ideal environment for conception, minimizing side effects, risks, and complication.

We believe that this patient-first philosophy, coupled with the higher success rates, is the best way to provide top care for anyone who comes to Hanabusa IVF. Using less medications, for us, is about safety, comfort, and ultimately helping you to have the healthiest pregnancy possible.

Key points of Mini IVF:

  • Low medication stimulation protocols
  • Egg retrievals that avoid intravenous sedation or general anesthesia
  • Using the smallest needle possible to avoid bleeding complications and lowering discomfort after egg retrieval
  • Culturing embryos to blastocyst stage to reduce poor quality embryos, failed transfers, and miscarriages
  • Possible Embryo freezing if fresh transfer is not ideal
  • Vitrification (freezing technique created in Japan) to optimize embryo survival
  • Minimal/no medication during embryo transfer
  • Single embryo transfer to minimize risk associated with multiple implantations

Minimal Stimulation IVF

Similar to traditional IVF, patients in minimal stimulation treatment will go through:

  • Ovulation Induction
  • Egg Retrieval
  • Fertilization
  • Embryo Culture
  • Embryo Transfer

However, Mini IVF employs far less medication to stimulate the ovaries in order to produce a few eggs whereas a traditional IVF uses more amounts of medication to produce multiple eggs for retrieval. Mini IVF treatment aims to get only 3 to 5 high-quality eggs to conceive a healthy baby. Although more eggs are produced in a traditional IVF cycle, not only is the quality lower, but also most of the eggs are discarded since patients only use a few.

Less Medication, Less Risk

Mini IVF protocols using low-doses of medication makes treatment more affordable than traditional IVF. The expensive injectable fertility drugs substantially increase the cost of IVF. However, Mini IVF employs the relatively inexpensive fertility drug, clomiphene citrate and lower doses of fertility drug injections. It enables more patients to afford IVF treatment to conceive a baby.

As Mini IVF uses less medication for stimulation, it decreases discomfort, reduces risk of Ovarian Hyperstimulation Syndrome (“OHSS”), and minimizes the risk of ovarian and endometrial cancer from high-dose fertility drugs. Patients also can benefit from fewer days of monitoring whereas a traditional IVF requires numerous office visits for monitoring.

Here are some of the advantages of Minimal Stimulation IVF available at Hanabusa IVF’s San Diego fertility clinic:

  • Fewer daily injections
  • Lower costs
  • Fewer days of monitoring
  • Less discomfort
  • Reduction of ovarian hyperstimulation syndrome
  • Minimizing the risk of ovarian and endometrial cancer
Patient Testimonials
  • "We are very happy to announce the birth of our son! The embryo that was tested for PGT but came back “unknown” for result turned out to be a very healthy boy! It took a lot of testings/procedures ..."

    - Submitted By Sk
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  • "I wanted to send you a personal note to express my sincerest gratitude for making our dreams come true. Before I found Hanabusa, we thought there was no chance we would be able to have a family. We ..."

    - Submitted By SA
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  • "Thank you everyone. The team here will always be apart of making my journey worthwhile. You all have been so supportive and great and took really great care of me. Thank you Dr. Chang for ..."

    - Submitted By PS
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  • "Just wanted to take a moment and thank each and everyone of you for spending so much time even through all these changes the attention to detail and the attention that you have paid me is greatly ..."

    - Submitted By B.P. Proud Surrogate
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  • "Thank you for taking such amazing care of us! And thank you for coming to meet us on a Saturday night for emergency medication after CVS Caremark and UPS messed up! I have been to several IVF clinic ..."

    - Submitted By LC
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  • "Every single person I had interactions with in this practice has been completely professional, knowledgeable, and empathetic. It’s a combination you rarely see in doctor’s offices. I could not ..."

    - Submitted By KG
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  • "We just celebrated our healthy baby girl's one month birthday, all thanks to Dr. Chang and his wonderful staff. Dr. Chang is the best and most trustworthy doctor I have ever encountered. He actually ..."

    - Submitted By MH
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  • "As doctors go, Dr. Chang is probably my biggest hero. He did not rush through our visits. He took the time to answer our questions (and I always had lots). He explained things clearly but simply. He ..."

    - Submitted By Anonymous
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  • "Dr. Chang is different from other doctors, especially in the IVF field. He listened to us with an open mind. For five years we struggled to conceive. We met doctor after doctor and the failures and ..."

    - Submitted By J&J
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  • "On my long and difficult journey to motherhood I could not have imagined a better doctor than Dr. Chang and I consider myself incredibly lucky that I found him. Before joining his clinic as a patient, ..."

    - Submitted By HR
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