

Preimplantation Genetic Testing (PGT) is an optional step in IVF that can provide genetic information about embryos before transfer. Depending on the type of testing, PGT may help identify embryos with certain chromosomal findings or specific inherited genetic conditions—so you and your care team can make more informed transfer decisions.
At Hanabusa IVF, PGT is always your choice. We’ll never pressure you into extra testing—instead, we’ll explain what PGT can and can’t tell you, and whether it may be helpful based on your age, diagnosis, personal and family history, and your goals. That way, you can choose the right level of information without added cost or complexity you don’t need.

We help you choose the right test type (if any), understand what results do and don’t mean, and turn that information into a clear transfer strategy.
We weigh benefits and tradeoffs based on your embryo expectations, age, diagnosis, and goals.
We explain what each PGT type can and cannot tell you, in plain language.
We integrate PGT into embryo culture, biopsy timing, and vitrification strategy intentionally.
We help translate results into an action plan—what to transfer first, what to consider next, and what questions to ask.
For DOR/POI, fertility after 40, or prior losses, we help you decide whether PGT adds meaningful clarity or adds unnecessary burden.

Clarify your goals (reduce miscarriage risk, avoid a known condition, improve transfer confidence)
Review personal/family history and any prior IVF/PGT outcomes
Identify which testing type(s) fit your situation: PGT-A, PGT-M, PGT-SR, and/or PGT-P
PGT-M / PGT-SR: genetic counseling + recordsPGT-M / PGT-SR: genetic counseling + records review (prior reports, carrier screening, karyotypes)
Create any required lab build steps (e.g., family sample coordination when needed)
Confirm timelines so testing is ready when embryos reach biopsy stage review (prior reports, carrier screening, karyotypes)
Create any required lab build steps (e.g., family sample coordination when needed)
Complete your IVF cycle (stimulation → retrieval)
Fertilize eggs (IVF or ICSI as appropriate)
Culture embryos to the stage appropriate for biopsy planning (typically blastocyst)
Biopsy a small sample of cells from each embryo (performed by the embryology team)
Freeze embryos after biopsy so results can return before transfer planning
Biopsied cells are sent to the genetics lab
Testing is performed based on your selected type(s):
PGT-A: screens chromosome copy number (aneuploidy)
PGT-M: tests for a specific single-gene condition
PGT-SR: evaluates chromosomes when a structural rearrangement is known/suspected
PGT-P: evaluates polygenic risk scores (when chosen)
Review results with your care team (and genetics counselor when appropriate)
Create a clear embryo transfer order based on results, embryo quality, and your goals
Discuss any limitations and what results mean for next steps
Choose the FET approach that fits your body and timeline (natural/modified natural/medicated)
Prepare the uterine lining and schedule transfer to match embryo stage and receptivity
Plan single embryo transfer when appropriate, guided by your clinical plan and results

PGT can help reduce uncertainty for certain patients—especially when there’s a known genetic risk or a higher chance of chromosomal issues. It can support more confident embryo selection and help some patients avoid transferring an embryo affected by a tested condition. But it also adds time, cost, and complexity—so it should be used when it truly improves your decision-making.

You are 35+ and want more information about chromosomal risk (case dependent)
You’ve had recurrent pregnancy loss or repeated failed transfers (case dependent)
You or your partner are carriers of a known genetic condition (PGT-M)
You have a known chromosomal rearrangement (PGT-SR)
You want a clearer embryo selection strategy before transfer
You expect a very small number of embryos and testing may not improve the overall chance of success (case dependent)
You want to minimize additional steps and move to transfer sooner
Cost or timeline makes PGT a poor fit right now (we’ll help you weigh options)

PGT type (PGT-A vs. PGT-M vs. PGT-SR)
Number of embryos biopsied/tested
Genetics lab fees
IVF lab steps required (biopsy + vitrification)
FET cycle costs for transfer
PGT-M setup: may require additional family testing and probe creation (case dependent)
Often included: embryo biopsy (varies by package/clinic structure)
Often separate: genetics lab testing fees, medications, monitoring, embryo storage, FET cycle costs

PGT does not increase embryo quality—but it may improve decision-making about which embryo to transfer first and can reduce the chance of transferring an embryo affected by certain tested findings. Outcomes still depend on embryo development, uterine factors, and overall health history.
Age and egg/embryo quality
Number of embryos available for testing
Test type and the specific indication (A vs. M vs. SR)
Uterine lining and receptivity at transfer
Transfer strategy and embryo stage
PGT stands for Preimplantation Genetic Testing—genetic testing performed on embryos created through IVF before transfer.
The most common types include PGT-A (chromosomal screening), PGT-M (single-gene conditions), and PGT-SR (structural chromosomal rearrangements).
PGT-A screens embryos for chromosomal aneuploidy (extra or missing chromosomes), which can be more common with increasing maternal age.
PGT-M tests embryos for a specific inherited genetic condition when one or both parents are known carriers (or affected), such as certain single-gene disorders.
PGT-SR is used when a parent has a known structural chromosome rearrangement (like a translocation) to help identify embryos less likely to be affected.
No. PGT can provide helpful information for embryo selection, but implantation and pregnancy still depend on many factors including embryo biology, uterine receptivity, and overall health.
With modern vitrification and experienced embryology teams, survival rates are generally very high. Your care team can explain what to expect based on your embryo plan.
Usually, yes. Because embryos are biopsied and frozen while testing is performed, transfer typically happens in a later frozen embryo transfer (FET) cycle.
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Age 40+ or time feels limited
Prior IVF didn’t respond as hoped
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Male factor needs ICSI or TESE
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